(file opens in new tab)
Vitamin C Clinical Studies
Marginal vitamin C status is associated with reduced fat oxidation during sub-maximal exercise in young adults
"Low vitamin C status may partially explain the inverse relationship between vitamin C status and adiposity and why some individuals are unsuccessful in their weight loss attempts. . . . These preliminary results show that low vitamin C status may reduce fat oxidation during submaximal exercise and that reduced fat oxidation during exercise was related to fatigue. It is possible that increased fatigue and less reliance on fat as a fuel during activity may influence eventual weight gain. Thus, in addition to emphasizing calorie control and physical activity, attention to specific diet components such as vitamin C may be necessary for effective weight management."
[Carol S. Johnston et al, Marginal vitamin C status is associated with reduced fat oxidation during submaximal exercise in young adults, Nutrition & Metabolism (2006) 3:35]