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Rhubarb Root Clinical Studies

Study #1


“Morphological analysis revealed that rhubarb could promote proliferation of goblet cells within intestinal mucosa, which secrete a great deal of mucus. The mucus can prevent endotoxin absorption, inhibit bacteria adherence to intestinal epithelial cell and bacterial translocation. Some researches revealed that rhubarb could promote excretion of endotoxin within gut, prevent bacterial overreproduction and maintain balance of the bacteria flora12,13. Rhubarb could also promote excretion of bile which can combine with endotoxin and inhibit endotoxin absorption.”


[De Chang Chen et al, Protective effect of rhubarb on barrier of intestinal mucosa, China National Journal of New Gastroenterology, 1997, 3(2):81-83]  


Study #2


“Chinese herbalists have relied on rhubarb rhizomes (roots) for thousands of years. The roots contain anthraquinones that act as stimulant laxatives and tannins that act as astringents. Case series support the Chinese use of rhubarb to treat gastric ulcers and chronic renal failure, toothaches and pregnancy-induced hypertension.


. . .


“Numerous case series report the effectiveness of rhubarb as a cathartic and stool softener. Case series and one randomized trial support the use of rhubarb as a therapy for chronic renal failure. Several case series support its use in treating bleeding ulcers in adults. In a randomized controlled trial, rhubarb extracts reduced the rate of pregnancy-induced hypertension.”


[Kathi J. Kemper MD MPH, Rhubarb (Rheum officinale, R. palmatum) Clinical Information Summary, The Longwood Herbal Task Force, August 1999, at mcp.edu/herbal/default.htm]


Study #3


“MEDICINAL RHUBARB (Rheum officinale or Rheum palmatum, also known as Turkey Rhubarb) is related to the garden rhubarb used for food, but it has much more of the active ingredients. The herbal medicine comes from the roots of the plant. It is available in tablets, tinctures (in alcohol), and as the dried, powdered root. 


[Andey Amata-Kynvi BSN RN, Rhubarb Patient Fact Sheet, The Longwood Herbal Task Force, September 1999, at mcp.edu/herbal/default.htm]

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