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Lactobacillus rhamnosus Clinical Studies

Study #1


"Dietary consumption of L. rhamnosus HN001, in a base of low-fat milk or lactose-hydrolyzed low-fat milk, appears to enhance systemic cellular immune responses and may be useful as a dietary supplement to boost natural immunity"


[ Ying-H., Sheih et al, Systematic Immunity-Enhancing Effects in Healthy Subjects Following Dietary Consumption of Lactic Acid Bacterium Lactobacillus rhamnosus HN001, Jounral of the American College of Nutrition, January 2001,

Vol 20, Issue 2, pp. 149-56]  


Study #2


"Probiotics are defined as live microorganisms that, when administered in adequate amounts, confer a health benefit on the host. There is now mounting evidence that selected probiotic strains can provide health benefits to their human hosts. Numerous clinical trials show that certain strains can improve the outcome of intestinal infections by reducing the duration of diarrhea. Further investigations have shown benefits in reducing the recurrence of urogenital infections in women, while promising studies in cancer and allergies require research into the mechanisms of activity for particular strains and better-designed trials"


[Reid, Gregor, et al. "Potential uses of probiotics in clinical practice." CLINICAL microbiology Reviews 16.4 (2003): 658-672.]


Study #3


"ultiple mechanisms of action have been postulated, including lactose digestion, production of antimicrobial agents, competition for space or nutrients, and immunomodulation. We have reviewed recent studies of probiotics for the treatment and control of infectious diseases. Studies of pediatric diarrhea show substantial evidence of clinical benefits from probiotic therapy in patients with viral gastroenteritis, and data on LGG treatment for Clostridium difficile diarrhea appear promising. However, data to support use of probiotics for prevention of traveler's diarrhea are more limited. New research suggests potential applications in vaccine development and prevention of sexually transmitted diseases."


[Alvarez-Olmos, Martha I., and Richard A. Oberhelman. "Probiotic agents and infectious diseases: a modern perspective on a traditional therapy." Clinical Infectious Diseases 32.11 (2001): 1567-1576.]

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