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Garcinia Cambogia Clinical Studies

Study #1


"In this study we assessed the efficacy of HCA with respect to energy intake and satiety, hypothesizing that, when HCA is effective in reducing energy intake, satiety is sustained.


. . .


Summarizing, we showed that daily administration of a relatively low dosage of HCA (900 mg=day), during 2 weeks, reduced energy intake in overweight subjects, while satiety was sustained."


[MS Westerterp-Plantenga and EMR Kovacs, The effect of (-)-hydroxycitrate on energy intake and satiety in overweight humans, International Journal of Obesity, 2002, 870–872]


Study #2


“A statistically significant loss of weight was observed over the 12-week study period in both the active (t= 7.80, p< 0.001) and placebo (t= 5.65, p< 0.001) treatment groups. The mean loss with active treatment was 3.7 ± 3.1 kg whereas the value was 2.4 ± 2.9 kg for the placebo group. The difference in weight loss between groups was also statistically significant (t= 2.26, p= 0.026).   . . . the reduction in waist circumference was significant (active = —.96 cm, placebo =—2.22 cm (t= 2.72, p= 0.008)).” 


[Richard D. Mattes and Leslie Bormann, Effects of (—)—hydroxycitric acid on appetitive variables, Physiology & Behavior, 2000, 71:87-94]


Study #3


[How Calcium (Ca) and Potassium (K) work with Hydroxycitric Acid (HCA):] “Ca2+ ions are involved in weight management by increasing lipid metabolism, enhancing thermogenesis, and increasing bone density. K+, on the other hand, increases energy, reduces hypertension, increases muscle strength and regulates arrhythmias. Both Ca and K act as buffers in pH homeostasis. HCA-SX has been shown to increase serotonin availability, reduce appetite, increase fat oxidation, improve blood lipid levels, reduce body weight, and modulate a number of obesity regulatory genes without affecting the mitochondrial and nuclear proteins required for normal biochemical and physiological functions.” 


[Bernard W. Downs et al, Bioefficacy of a novel calcium-potassium salt of (−)-hydroxycitric acid, Mutation Research 579 (2005) 149–162]

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