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Garcinia Cambogia Clinical Studies
"In this study we assessed the efﬁcacy of HCA with respect to energy intake and satiety, hypothesizing that, when HCA is effective in reducing energy intake, satiety is sustained.
. . .
Summarizing, we showed that daily administration of a relatively low dosage of HCA (900 mg=day), during 2 weeks, reduced energy intake in overweight subjects, while satiety was sustained."
[MS Westerterp-Plantenga and EMR Kovacs, The effect of (-)-hydroxycitrate on energy intake and satiety in overweight humans, International Journal of Obesity, 2002, 870–872]
“A statistically significant loss of weight was observed over the 12-week study period in both the active (t= 7.80, p< 0.001) and placebo (t= 5.65, p< 0.001) treatment groups. The mean loss with active treatment was 3.7 ± 3.1 kg whereas the value was 2.4 ± 2.9 kg for the placebo group. The difference in weight loss between groups was also statistically significant (t= 2.26, p= 0.026). . . . the reduction in waist circumference was significant (active = —.96 cm, placebo =—2.22 cm (t= 2.72, p= 0.008)).”
[Richard D. Mattes and Leslie Bormann, Effects of (—)—hydroxycitric acid on appetitive variables, Physiology & Behavior, 2000, 71:87-94]
[How Calcium (Ca) and Potassium (K) work with Hydroxycitric Acid (HCA):] “Ca2+ ions are involved in weight management by increasing lipid metabolism, enhancing thermogenesis, and increasing bone density. K+, on the other hand, increases energy, reduces hypertension, increases muscle strength and regulates arrhythmias. Both Ca and K act as buffers in pH homeostasis. HCA-SX has been shown to increase serotonin availability, reduce appetite, increase fat oxidation, improve blood lipid levels, reduce body weight, and modulate a number of obesity regulatory genes without affecting the mitochondrial and nuclear proteins required for normal biochemical and physiological functions.”
[Bernard W. Downs et al, Bioefficacy of a novel calcium-potassium salt of (−)-hydroxycitric acid, Mutation Research 579 (2005) 149–162]